研究於老化及各種神經病變於神經影像之表現

計畫名稱:研究於老化及各種神經病變於神經影像之表現

所屬單位:醫學系放射線科

研究團隊:Brain e-bank

計畫主持人:廖漢文

資源需求:FreeSurfer, FSL, SPM

使用期間:2012/06~

研究主題:
研究於老化及各種神經病變於神經影像之表現

研究內容概述:
在基礎與臨床神經科學中,使用MRI量化腦部構造及容量已經開始有一些重要的應用。我們計畫使用電腦運算分析腦部影像以達成以下目標:
1. Set up the effect of age on the brain in different cortical and subcortical regions with automated measurement of their thickness and volume. As well as the possibility set up the development of the different brain regions in time period.
2. Set up the effect of gender on the brain in different cortical and subcortical regions with automated measurement of their thickness and volume.
3. Set up the effect of different machine, imaging pulse sequences, aging of the machine, and different magnetic field in the measurement of the cortical and subcortical regions of brain.
4. Set up the effect of leukoaraiosis in different grades in the measurement of the cortical and subcortical regions of brain and their correlation with clinical manifestation.
5. Set up the effect of different neurodegenerative disease in the measurement of the cortical and subcortical regions of brain.
6. Set up the effect of destructive brain disease such as infarction, traumatic and post-operative encephalomalacia in the measurement of the cortical and subcortical regions of brain.

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